Oncology test menu

Oncology Microarray, Oncology Testing Laboratory

Assure™ SNP Microarray utilizes a high resolution single nucleotide polymorphism (SNP) analysis for the detection chromosomal alterations. This permits for accurate detection of both large genome copy-number changes and individual genes associated with cancer. Chronic lymphocytic leukemia (CLL) and myelodysplastic syndromes (MDS) are especially suitable for Assure™ SNP Microarray analysis because of the high incidence of dosage-related clonal changes that have been proven to have an influence on patient outcomes.

Assure™ SNP Microarray detects copy number aberrations seen by karyotype and FISH.  Additionally it provides faster, higher-resolution results than standard karyotyping and can help detect clinically significant cryptic aberrations that common FISH panels may not target.   Assure™ SNP Microarray quickly identifies copy number changes in hematologic malignancies with a single study.

Specimen Requirements

Sample Type Chromosome
CMA Direct
Peripheral Blood 5-10 ml 5-10 ml
A completed requisition and consent form should be sent with each sample.

 Reporting of Results

  • Copy number gain/losses of >50Kb within clinically significant genes or regions
  • Copy number loss of >200 kb or gain >500 kb outside known clinically significant regions with at least one OMIM annotated gene or within a region of clear clinical significance
  • Identification of UPD and consanguinity