Ewings’ sarcoma Info

t(11;22)(q24;q12)
The t(11;22) is a relatively specific chromosome rearrangement found in over 80% of Ewings’ Sarcomas.  This rearrangement has also been described in neurogenic tumors such as peripheral neuroepithelioma, Askins’ tumor, and esthesioneuroblastoma.  Trisomy 8 is a common secondary chromosome change.