Amniotic Fluid Chromosome Analysis Testing
Indications for Amniotic Fluid Chromosomal Analysis
- Abnormal first trimester screening result
- Abnormal NIPT result
- Advanced maternal age (>35 years of age)
- Previous pregnancy with chromosomal abnormality
- Recurrent spontaneous miscarriage
- Family history of a chromosomal abnormality
- Abnormal maternal serum screening results
- Abnormal ultrasound findings
Specimen Requirements
15-20cc amniotic fluid (less if early amniocentesis)
Collection Procedure
Discard the first 2 ml of fluid to reduce the risk of maternal cell contamination. Aseptically transfer the specimen into sterile plastic conical tubes labeled with patient’s name and date of birth. A completed test requisition form must be included with every sample. A transport kit is available upon request. To learn more about the Amniocentesis lab testing please call us today.
Specimen Container
Sterile 15ml screw-cap container
Methodology
In situ culturing of amniocytes to identify both numerical and structural chromosome abnormalities
Transport Temperature
Room temperature (DO NOT refrigerate, freeze or centrifuge)
Causes for Rejection
- Frozen specimen, excessive amounts of blood, inappropriate container
- Delay in transport >72 Hr
Turnaround Time
5-10 days