Products of Conception (POC) Chromosome Analysis

Indications For Products of Conception

Miscarriage or fetal demise coupled with:

  • Advanced maternal age (>35 years of age)
  • Previous pregnancy with chromosomal abnormality
  • Recurrent spontaneous miscarriage
  • Family history of a chromosomal abnormality
  • Abnormal maternal serum screening results
  • Abnormal ultrasound findings 

Collection Procedure

DO NOT handle tissues.  Sterility is critical to obtaining a result. Send sample in original collection container or transfer to a sterile screw top container and fill with sterile transport medium (DO NOT ADD FORMALIN), label with patient’s name and date of birth.  A completed test requisition form must be included with every sample.  Please call for required transport kit or to verify proper transport medium. 

Specimen Requirements

Fetal tissues, placental (CVS)

Specimen Container

DO NOT handle sample. Send in original collection container or a sterile screw-cap container containing transport medium.  Call client services for transport media (888-436-3633).

Transport Temperature

Room temperature (DO NOT refrigerate, freeze or centrifuge)


Laboratory Testing of Products of Conception (POC) involves culturing of fetal tissues to identify both numerical and structural chromosome abnormalities 

Causes for Rejection

Frozen specimen, no fetal tissue, inappropriate container (containing formalin), gross contamination 

Turnaround Time

7-14 days

For more information on Products of Conception and POC Chromosome Analysis, Please contact CytoGenX today.